Asia Life Sciences

Abstract : The utilization of both plant extracts and phytochemicals, with remarkable antimicrobial properties, can be of great importance for therapeutic applications, particularly in the treatment of diseases caused by Multidrug resistant microorganisms. The frame work of the current study was mainly designed to study the efficacy of some naturally existing plant derived, fungal derived and algal derived antimicrobial substances against the multidrug resistant microorganisms isolated from diabetic foot lesions of the patients. The pus samples collected from diabetic foot lesion patients in a Tertiary care hospital were processed immediately in the Microbiology laboratory for the isolation and identification of pathogens through morphological, cultural and biochemical characterization. Antibiotic susceptibility pattern of isolated pathogens was checked by Kirby Bauer disc diffusion method using Clinical and Laboratory Standards Institute (CLSI) guidelines. Different naturally available compounds like Honey, spices, spirulina and mushroom were used to determine their antibacterial activity against the wound isolates through agar-well diffusion method at varying test concentrations against Staphylococcus aureus, Klebsiella pneumoniae, E. coli, Pseudomonas aeruginosa, Proteus mirabilis, Coagulase negative staphylococci, Enterococcus faecalis, E. coli 25922 and S.aureus 25927. The results obtained in the current study propose that bioactive and structurally diverse fungal metabolite i.e. mushroom extracts, herbal products like spices showed mild antibacterial activity while to honey and spirulina at highest concentrations. The study helps in the development of valuable pharmaceutical products and may be one of the better options for treating the infections caused by multidrug resistant bacterial isolates

Abstract :

Ultraviolet (UV) light has been an important source in human health throughout human evolution. However, modern lifestyles, indoor jobs, cultural myths, religious beliefs and the increase of globalization has drastically reduced UV light exposure in humans, amounting to growing cancer rates, diseases and worldwide health deterioration. This commentary details various human activities, lifestyles and their effects on health worldwide. It also examines misinterpreted findings pertaining to the lack of UV light exposure that could further undermine existing health issues. UV light producing technologies to reduce adverse effects on human health are currently being used and are very effective. They are safer than sunlight, available at any time, inexpensive and could reduce healthcare costs by decreasing drug use and extensive cancer therapies. Public health agencies and healthcare providers throughout the world should make individuals aware of UV light exposure benefits.