Asia Life Sciences

This study was carried out to investigate the phytochemical screening, antioxidant activity, and anxiolytic-like effects of the ethanolic extract of Melissa officinalis L. (MO) (Family of Lamiaceae). The antioxidant activity of MO was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis-3- ethylbenzothiazoline-6-sulfonic acid (ABTS) methods. The antioxidant activity and phytochemical screening were performed on the ethanol extract of MO and then was orally administered to rats at doses of (30, 300, and 500 mg/kg daily) during the experimental period of 10 days for behavioral tests by using the elevated plus maze (EPM), and biochemical studies. Phytochemical screening revealed the presence of alkaloids, flavonoids, saponins, steroids, triterpenoid and tannins. The phenol concentration was (46.90 mg EAG/g DM), and flavonoids were found to be (15.06 mg EQ/g DM). DPPH radical scavenging assay showed potent antioxidant power with IC50 values of 15.44 µg/ml and ABTS (137.45 µg/ml). The sub-chronic administration of Melissa officinalis L. ethanol extract increased significantly the percentage of entries and the time spent on the open arms compared with a control group. The levels of malondialdehyde (MDA) and nitric oxide (NO) were significantly reduced by MO ethanol extract. The present study reveals that Melissa officinalis L. can be used as a potential source of natural antioxidants to prevent oxidative stress, and suggests that it possesses anxiolytic-like effect

The article explores the benefits of using computer technology in the educational process and emphasizes their ability to increase the motivation of foreign medical students to study. Using the latest technologies in the educational process is a demand of time. Intensifying the interest to the discipline and improving the quality and level of knowledge of students is the purpose of such using. The necessity and importance of on-line education at the current stage of society development is substantiated. Using effective techniques and methods of online learning, creating a variety of online courses, engaging students in an independent creative process - this is the optimal way to update the internal reserves of the educational process. The role of students' independent work in the educational process is determined. It is noticed that the independent work of students requires the same organization and methodological support as the traditional class work. The peculiarities of the content of independent work of foreign medical students are revealed and their communicative needs are determined. In accordance with the subjects of the educational programs for specialists in the field of knowledge 22 "Health care", specialty 222 "Medicine" and according to the communication needs, EDX on-line platform was selected and created for creating and implementing online special courses for independent work of foreign students at different stages of study. The structure of individual online special courses is analyzed, the purpose, tasks and results of each of them are highlighted. The subject, distribution of classes, structure, linguistic, speech and communication material of the on-line special course "Introduction to the specialty: scientific speech" are characterized. The specificity, orientation, purpose and specifics of the task of the on-line special course "Professional communication: doctor – patient" are revealed. The conclusions about the necessity and appropriateness of the application of the specified online special courses in the process of preparation of foreign students in medical institutions of higher education.